Research is an integral component of the Intensive Care Unit at Barwon Health. It ensures we continually understand how best to treat patients and adapt to changes in health science. Conducting research in the critically ill requires particular skills, experience and sensitivity. Our dedicated and experienced ICU research nurses are a pivotal interface between clinicians, patients, families, coordinating centres and hospital research governance processes. Our monthly research meeting allows ICU staff to be updated on the progress of all research projects and consider proposals for new studies. This forum is an effective means of engaging clinical staff and identifying appropriate future studies and collaborations. During 2018 / 2019, there were 1,735 patients admitted to ICU. Overall there were 2,688 episodes of screening, and 134 ICU patients (7.7%) participated in clinical research. This is higher than the prior year (4.5%), and higher than the rate reported in Australia / New Zealand (approx. 2%).

Medical Director of Reasearch: Dr Neil Orford

Research Nurse Coordinators: Michelle Horton, Jemma Tricky

  • MegaRox: Adaptive randomisation or liberal vs conservative oxygen provision for all emergently mechanically ventilated adults
  • HAS FLAIR II: Comparing 20% Albumin solution vs crystalloid as bolus fluid therapy post cardiac surgery
  • REMAP-CAP: Platform Trial of interventions for community acquired pneumonia
  • SPRINT SARI: Short Period Incidence study of Severe Acute Respiratory Infection
  • ECMO-CARD: Extracorporeal Membrane Oxygenation for 2019 Novel Coronavirus Acute Respiratory Disease
  • BONEZONE: Compares the effect of subcutaneous denosumab or IV zoledronic acid to placebo on change in bone mineral density in women the year after critical illness
  • REVISE: Compares 40mg IV pantoprazole vs placebo for stress ulcer prophylaxis in critically unwell patients
  • TEAM: early mobilisation for ventilated patients, early activity vs standard care